The area was defined to half the height of the peak velocity, to maximize accuracy. The images were acquired using a 1.5 T MR unit with a phase-contrast sequence in an oblique-transversal plane perpendicular to the Sylvius aqueduct codified to 20 cm/s and with 27 observations per cardiac cycle by means of retrospective synchronization.
We have carried out a quantitative analysis of 38 subjects (19 healthy subjects and 19 patients with suspected idiopathic NPH). more A combination of good clinical selection with reliable quantification of diverse parameters that characterize the dynamics of cerebrospinal fluid (CSF) flow from phase-contrast magnetic resonance imaging may identify patients with idiopathic normal pressure hydrocephalus (NPH). No ot.Ī combination of good clinical selection with reliable quantification of diverse parameters that. Stroke volume and mean flow showed no false positive results and successful classification rates of 86% and 79%, respectively. RESULTS: Maximum diastolic velocity, mean flow, and stroke volume showed statistically significant differences that could be used to distinguish between NPH and CVD patients (P<.001). Discriminant analyses were performed to evaluate the classification capacity of both individual parameters and the combination of different parameters. All patients underwent a phase-contrast MRI study and several CSF flow and velocity parameters were measured at the aqueduct of Sylvius. METHODS: The study included 108 subjects, of whom 61 were healthy controls and 47, patients in the patient group, 19 had cerebrovascular disease (CVD) and 28 had NPH. more OBJECTIVES: The aim of this study is to evaluate the use of phase-contrast MR imaging to diagnose normal pressure hydrocephalus (NPH) and differentiate it from other neurological disorders with similar clinical symptoms. OBJECTIVES: The aim of this study is to evaluate the use of phase-contrast MR imaging to diagnose. It is possible to quantitatively describe the dynamic relations between intracranial fluids and infer the elastic behavior of the brain and spinal canal by using flow velocity maps obtained with phase contrast MRI. We calculated the indexes of compliance of the encephalic and medullary compartments in normal subjects. With respect to the input of arterial blood, the displacement of venous blood (22% and 38% of the cardiac cycle in the straight sinus and superior sagittal sinus, respectively) and of CSF (12% and 25% of the cardiac cycle in the C2-C3 perimedullary space and in the aqueduct of Sylvius, respectively) show the distribution of the pulsatility of the intracranial fluids. We calculated the amplitude parameters (systolic volume, mean flow, pulsatility and compliance indexes, absolute pressure gradient, and ratio of CSF volume per cycle) and temporal parameters (delays respect to arterial flow). Each study consisted of four phase contrast sequences: two to calculate the CSF (aqueduct of Sylvius and the C2-C3 perimedullary space) and two to calculate the blood flow (internal carotid and vertebral arteries, superior sagittal sinus, and straight sinus). We analyzed 15 healthy volunteers during the same time of day and using the same magnetic field strength (3T). more To estimate the dynamic relations between cerebrospinal fluid (CSF) and blood in the cerebral and spinal subarachnoid spaces and in the ventricles by quantifying phase contrast magnetic resonance imaging (MRI). To estimate the dynamic relations between cerebrospinal fluid (CSF) and blood in the cerebral and.
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